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Kukwezeleza Ndi Kugwiritsa Ntchito Kwa Ufa Wowumitsidwa Wachinjoka cha Njoka Pamsika Padziko Lonse
M'zaka zaposachedwa, mankhwala a biochemical hemostatic makamaka opangidwa ndi enzyme yauvuni wa njoka akhala akugwiritsidwa ntchito kwambiri m'chipatala ndipo akukhala njira yayikulu yochizira mankhwala.
Mankhwala a hemostatic, omwe amadziwikanso kuti procoagulant mankhwala, nthawi zambiri amakhala mankhwala omwe amathandizira kuti magazi azilumikizana, kuphatikiza kufulumizitsa kuthamanga kwa magazi kapena kuchepetsa capillary permeability kuti magazi asiye kutuluka.Iwo ndi waukulu ndi wofunika achire mankhwala kwa matenda mankhwala a hemorrhagic matenda kapena magazi boma.
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Zotsatira Zisanu ndi Ziwiri za Antithrombotic Zinagwiritsidwa Ntchito
Pali mitundu iwiri ya mapuloteni mu utsi wa njoka, umodzi womwe ndi wowongoka.Enzayimu yomwe imasungunula fibrin (protolysin) imatchedwa fibrin (protolysin) enzyme (Yachidule ya plasminase,fi b ri no L yt I cenz YM E, FLE).Kuwonjezera kunyozetsa fibrin ndi fibrinogen, Palibe kutsegula kwa plasminogen mu thupi la munthu, palibe hydrolysis wa zinthu zina coagulation Ndipo kupatsidwa zinthu za m`mwazi nembanemba, ali zoonekeratu antithrombotic kwenikweni.Zina ndi kudzera pa suppressionProthrombin imayendetsedwa kuti ichedwetse kukhazikika kwa coagulation ndipo ilibe ntchito ya enzyme.
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Kugwiritsa Ntchito Utsi Wa Njoka Kuletsa Kutaya Magazi Ndi Anticoagulation
Mu 1981, defibrase yotengedwa ndi kupangidwa ndi Kunming Institute of Zoology, Yunnan, China, ku chiwopsezo cha njoka ya pentameter yaku China idadutsa kuwunika kwaukadaulo ndipo idagwiritsidwa ntchito pochiza milandu ya 333 ya mitsempha yamagazi, kuphatikiza milandu 242 ya thrombosis yaubongo. mlingo wogwira mtima wa 86.4%.The agkistrodon agkistrodon acidase, yopangidwa ndi China Medical University ndi Shenyang Pharmaceutical College, yakhala ikugwiritsidwa ntchito pochiza occlusives ya mitsempha ndi zotsatira zogwira mtima zachipatala.Njoka poizoni Laboratory ya China Medical University anayamba njoka ya njoka antacid enzyme, amene angathe kuchepetsa lipids magazi, dilate mitsempha, kuchepetsa zili thrombin m'magazi, kuonjezera prostacyclin, ndi kumasuka yosalala minofu ya mitsempha.Ndikoyenera kwa anticoagulant thrombolytic kukonzekera.
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Tulutsani Essence Ya Utsi Wa Njoka Mu Ufa Wowumitsidwa Wa Utsi Wa Njoka
1. Peptide yauvuni wa njoka yomwe ili ndi ufa wowuma wowuma ndi njoka yamankhwala ndi ntchito yachipatala, yomwe imatha kulimbikitsa ntchito yokonzanso zotchinga ndikuchedwetsa kubadwa kwa makwinya.Wonjezerani kusungirako madzi pakhungu, pangani khungu kukhala lolimba komanso zotanuka
2. Kukonza khungu, kuthandizira kuzimiririka ndikuwongolera mizere yabwino, kutseka bwino madzi ndi kunyowa, kuyeretsa pores, kudyetsa khungu ndikupangitsa khungu kukhala losalala komanso lowala.
3. Maonekedwe onyezimira akhungu, pansi pakhungu, osavuta kuyamwa, yambitsa ma cell, makwinya osalala, amawonjezera kusungunuka kwa khungu.
4. Kuzimiririka makwinya ndi kumangitsa, kukonza khungu lowonongeka ndi kumangitsa
Khungu, zimasuluka mizere yabwino, limbitsa zotchinga pakhungu, chepetsani khungu louma komanso losalimba
Thandizani kukonzanso khungu, kukonza khungu, kuzimiririka ndikuwongolera mizere yabwino, kutseka bwino madzi ndi kunyowa, kuyeretsa pores, kulimbitsa khungu, kupangitsa khungu kukhala losalala komanso lowala. -
Ululu wa Njoka Wochokera ku Agkistrodon (Njoka ya masitepe asanu) Uyenera Kuthandizidwa Ndi Seramu Yothira Magazi
Mayesero awiri a zachipatala anachitidwa, mayesero oyendetsedwa ndi placebo komanso mayesero oyendetsedwa bwino.Mabala onse anali akutuluka magazi chifukwa chodulidwa khoma la m'mimba pochita opaleshoni ya m'mimba.Zizindikiro zazikulu zochizira zinali kutaya magazi, nthawi ya hemostasis ndi kutaya kwa magazi pagawo lililonse.Mwachisawawa placebo m'mayesero azachipatala mu milandu 180 ya anthu: kuchuluka kwa mfundo zongofanana ndi placebo, 2 u ndi 3 u magulu atatu, preoperative mphindi 15-20 limodzi mtsempha wamagazi mlingo, zotsatira zikusonyeza izi Mlingo awiri mu magazi, nthawi magazi ndi. kutayika kwa magazi pa chiwerengero cha chigawo cha unit kunali kopambana kuposa placebo, koma palibe mgwirizano wokhazikika pakati pa magulu awiri.Mu mayesero abwino kulamulira, panali 324 odwala mu experimental gulu ndi 108 odwala mu ulamuliro gulu, ndi mlingo umodzi wa 2U anapatsidwa mu experimental gulu 15-20 mphindi pamaso opaleshoni ndi limodzi mtsempha wa magazi jekeseni.Palibe zoyipa zomwe zidawonedwa m'mayeso omwe ali pamwambawa.
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Snake Venom Application Anti-cancer effect
Zopangira Ufa wouma wa utsi wa njoka wopangidwa ndi kampani yathu umapangidwa kuchokera ku utsi wa agkistrodon.
Ufa wowuma wowuma utsi wa njoka umagwiritsidwa ntchito kwambiri pazamankhwala, zankhondo, kukongola ndi zina.Ufa wowuma wowuma wa utsi wa njoka umagwiritsidwa ntchito mosiyanasiyana komanso chiyembekezo chakukula. -
Analgesia Of Njoka Ufa Wowumitsidwa Wowuma
Kugwiritsa ntchito utsi wa njoka mu agkistrodon (njoka ya masitepe asanu): analgesia
Utsi wa njoka uli ndi ntchito zothamangitsira mphepo ndi kutulutsa mpweya, anticoagulation ndi antithrombus, kuchotsa fibrinogen, kuchepetsa kukhuthala kwa magazi, kukulitsa mitsempha yamagazi, kukonza ma microcirculation ndikutsitsa lipids m'magazi.Ululu wa agkistrodon agkistrodon uli ndi mankhwala ochuluka, omwe ali ndi zigawo za pharmacological zolimbikitsa kugwa, fibrinolysis, anti-cancer ndi analgesia.Ntchito zazikuluzikulu ndi:
1. Kuchepetsa ululu.
2. Kutsika kwa magazi.
3. Kutuluka magazi ndi anticoagulation.
4. anti-cancer zotsatira.
5. chithandizo cha thrombosis ndi vasculitis.
6. Chitani zilonda zam'mimba ndi mmatumbo.
7. ndi seramu yotsutsa magazi.
8. Kukonda usilikali ndi mankhwala osokoneza bongo -
Ufa Wowumitsidwa Wowuma Njoka Ntchito Zina
Agkistrodon agkistrodon imatulutsa poizoni wambiri, ndi michere yogwira ntchito yolemera, ndi mtundu wa Kafukufuku wamakono amangokhala ndi thrombin - monga kafukufuku Kuwonjezera apo, zotsatira za antitumor zakhala zikudziwika, pamene maphunziro ena a thupi kapena a pharmacological afanizidwa Pang'ono;Choyamba, a.agkistrodon yakhala ikugwiritsidwa ntchito kwa mphepo ndi dehumidification kwa nthawi yaitali Mphamvu ya pharmacological ya mankhwalawa iyenera kuwerengedwa.Kachiwiri, utsi wa njoka womwe ukugwiritsidwa ntchito pamsika wapano.
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Ululu wa Njoka Uli Ndi Mlandu Wogwiritsira Ntchito Kukongola Kwachipatala
Kuyesedwa kosalekeza kwa nthawi kumakhala ndi zotulukapo zambiri, ndipo pamene tikukula, tonsefe timakhala ovutika.Khungu lathu likasiya kuchulukana, timakhala ovutitsidwa ndi makwinya, mizere yabwino komanso makwinya.Seamax Cell regeneration Complex yokhala ndi mchere wa Dead Sea imapereka mayankho kukongola omwe akuwongolera pogwiritsa ntchito njira zapamwamba zasayansi.
Njirayi imatha kuyambiranso kukonzanso maselo, kuyambitsanso kukonzanso kwa khungu ndikuwonetsa khungu lathanzi.Ma peptides opangidwa ndi utsi wa njoka amayang'ana zochitika za neuromuscular kuti ziletse zolandilira minofu zomwe zimakwinya pakhungu ndikuyambitsa makwinya.
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Kugwiritsa ntchito jekeseni wa njoka ya hemagglutinin
Njoka ya hemagglutinin, yomwe ili ndi thrombin ndi thrombin, yakhala ikugwiritsidwa ntchito kwambiri pachipatala cha hemostasis m'zaka khumi zapitazi.Thrombin akhoza kulimbikitsa kupatsidwa zinthu za m`mwazi aggregation pa malo magazi, kulimbikitsa fibrinogen kuwonongeka, kupanga fibrin monoma, ndiyeno polymerize mu insoluble fibrin, kulimbikitsa thrombosis pa magazi malo;Thrombin imayendetsa prothrombin ndikufulumizitsa kupanga kwa thrombin, potero kumathandizira kutsekeka.
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Longshe Snake Industry Agkistrodon (Njoka ya masitepe asanu) ufa wa njoka
Zopangira Ufa wouma wa utsi wa njoka wopangidwa ndi kampani yathu umapangidwa kuchokera ku utsi wa agkistrodon.
Ufa wowuma wowuma utsi wa njoka umagwiritsidwa ntchito kwambiri pazamankhwala, zankhondo, kukongola ndi zina.Ufa wowuma wowuma wa utsi wa njoka umagwiritsidwa ntchito mosiyanasiyana komanso chiyembekezo chakukula.
