Kulekanitsa zigawo za anticoagulant ndi fibrinolytic kuchokera ku Agkistrodon acutus venom ndi momwe zimakhudzira magazi a coagulation system.

[Mwatsatanetsatane] Cholinga: Kuphunzira momwe ma thrombin-like and fibrinolytic enzymes olekanitsidwa ndi kuyeretsedwa kuchokera ku poizoni wa Agkistrodon acutus pamagazi a coagulation system.Njira: Ma enzymes onga thrombin ndi fibrinolytic adapatulidwa ndikuyeretsedwa kuchokera ku Agkistrodon acutus venom ndi DEAE-Sepharose CL-6B ndi Sephadex G-75 chromatography, ndipo zotsatira za onse pamilozera yamagazi a coagulation system zidawonedwa kudzera mu kuyesa kwa vivo.Results: Chigawo chimodzi cha thrombin-like ndi fibrinolytic enzymes chinasiyanitsidwa ndi kuyeretsedwa kuchokera ku Agkistrodon acutus venom, Maselo awo achibale awo ndi 39300 ndi 26600, motsatira.Kuyesa kwa vivo kwatsimikizira kuti ma thrombin-ngati ndi fibrinolytic enzymes ochokera ku Agkistrodon acutus venom amatha kutalikitsa nthawi yonse yamagazi yamagazi, kutsegulira pang'ono nthawi ya prothrombin, nthawi ya thrombin ndi nthawi ya prothrombin, ndikuchepetsa zomwe zili mu fibrinogen, koma gawo la thrombin- monga michere ndi wamphamvu, pamene fibrinolytic michere kusonyeza anticoagulant kwenikweni pa mlingo waukulu, Pomaliza: Thrombin ngati puloteni ndi fibrinolytic puloteni kuchokera Agkistrodon acutus venom zimakhudza magazi coagulation dongosolo nyama, ndipo kuphatikiza awiri ali ndi zoonekeratu anticoagulant kwenikweni.