Utsi wa njoka uli ndi zigawo zambiri za bioactive, makamaka protease ndi polypeptide
Amapanga pafupifupi 90% ~ 95% ya kulemera kouma kwa ululu wa njoka [l
Ndi chitukuko chosalekeza chaukadaulo, mapuloteni ambiri achilengedwe omwe amagwira ntchito muutsi wa njoka amayamba pang'onopang'ono
Wapatulidwa ndi kuyeretsedwa, ndipo anthu atero
Chitani kafukufuku wozama pankhaniyi ndi cholinga chogwiritsa ntchito mankhwala omwe ali ndi utsi wa njoka kwa anthu.
Pochiza matenda ofanana.Panopa, yogwira zosakaniza ogwira mankhwala ali njoka njoka
Kafukufuku wamankhwala ndi ntchito zachipatala zomwe zimachitika makamaka zimayang'ana kwambiri pa antithrombotic, hemostatic ndi hypoglycemic
Pressure, anti-cancer ndi painkillers.
L Antithrombotic mankhwala
Ma protease a njoka okhala ndi anti-thrombotic ndi thrombolytic zotsatira makamaka akuphatikizapo Ancelor.
Enzyme (hoe crod), batmxobin, defibrase (de coerase) ndi Agkistrodon acutus
Enzyme (autobin).Atatu oyambirira ndi a snaI [e venom
Thmmbin ngati ma enzyme, s Ⅷ.E), sVTLE ndi serine protease, chimodzimodzi ndi
Ili ndi arginine esterase ndi ntchito ya amidase - 1. Njoka ya njoka ya thrombin-ngati enzyme
Imagwira pa fibrinogen kumasula fibrinogen A kapena B, motero
Iwo akhoza coagulate ndi polymerization wa fibrin monoma mutu ndi mchira, chifukwa limasonyeza thrombin
Ntchito ndipo amatchedwa thrombin-ngati.Pa nthawi yomweyi, enzyme yofanana ndi thrombin ya njoka sichipezeka mwa anthu
Imayendetsa coagulation factor x Ⅲ mu vivo, ndipo fibrin monomer yopangidwa ndi hydrolysis yake imatha.
Mutu ndi mchira polymerization, koma sangathe kutulutsa mbali unyolo mtanda kulumikiza, amene n'zosavuta kuonongeka ndi chilengedwe reticuloendothelial dongosolo.
Mlingo wa plasma wa fibrinogen umachepetsedwa chifukwa cha phagocytosis kapena kuwonongeka kwa fibrinolytic system
Ili mu benign fibrinolytic state, motero imawonetsa anticoagulation ndi kupsinjika m'thupi
Fibrillation H1.Agkistrodon acutus enzyme ndi wa fibrinolytic enzyme, yomwe ndi fibrinolytic
Chidule cha enzyme [Erin (ogen) ol "icenzyme, FLE] ikhoza kugawidwa mu unyolo umodzi.
Zinc metalloproteinase ndi single-chain kapena double-chain serine protease, makamaka dzira lachitsulo la zinc.
Enzyme yoyera.Njoka poizoni fibrinolytic enzyme safuna kutsegula kwa activator, ndipo akhoza mwachindunji kudula ulusi.
Puloteni (protogen) imapanga hemofibrin, motero sizimayambitsa kuphatikizika “J.
Kuchokera ku ululu wa Agkistrodon halys (mwachitsanzo sek, № r [md ∞ to, ship) ku Malaysia
Ankylose yodzipatula inali yoyamba kugwiritsidwa ntchito pochiza matenda a thrombotic
SVTLE mankhwala.6 J. Pambuyo pa chitukuko cha Ancelose, idaphunziridwapo ndi mayiko ambiri
Ofufuza akukhulupirira kuti sV'11E ndiye mankhwala omwe amathandizira kwambiri pochiza matenda a thrombotic,
Kuphatikiza pa kugwiritsidwa ntchito pochiza zotumphukira thrombosis, itha kugwiritsidwanso ntchito pochiza venous thrombosis ndi chapakati venous thrombosis.
Pulse thrombosis imakhalanso ndi mphamvu yochiritsa "J.Pofika m'ma 1990, mayiko ambiri ndi zigawo
Qu Du ali ndi chidwi kwambiri ndi chithandizo cha pachimake cerebral ischemia ndi sitiroko ndi aclase, ndi
Pulojekiti ya ndalama: Ntchito ya Military Medical Science and Technology Youth Cultivation Project (13QNP068);Gulu lonse lankhondo “12
5 "ntchito yofufuza zamankhwala (cwslJ280);Chengdu Military Region "12th Five-year Plan" Medical Research
Ntchito zazikulu (B12026);Ntchito yofufuza zachipatala ya Chengdu Military Region panthawi ya 12th Year Planning
(C12062)
Chigawo cha wolemba: 650032 Kunming, Chengdu Military Region Center for Disease Control and Prevention (Zhang Zhixiao,
Hu Tingsong, Cui Qinghua, Zheng Ying, Fan Quanshui);Pathogens, School of Basic Medicine, Youjiang Medical College for Nationalities
Biology and Immunology Teaching and Research Office (Xie Zhenfeng)
Wolemba wofananira: Fan Quanshui, Imelo: fqsl68@126.com
Maphunziro angapo ang'onoang'ono azachipatala achitika.Mlozera woyeserera wogwiritsa ntchito mankhwala
Kuphatikiza apo, Ancelose angagwiritsidwe ntchito pochiza odwala omwe ali ndi vuto la ischemic koyambirira
Zimawonetsa zotsatira zabwino zochiritsira.Pambuyo pake, ndi magulu akuluakulu akhungu awiri, a placebo
Malinga ndi matenda mayesero, iye, etc. Pakuti 2613 milandu pachimake
Zotsatira za chithandizo chamankhwala cha odwala omwe ali ndi vuto logonana la ischemic adatsimikizira kuti odwala omwe ali mu gulu la cloroxobin
Chiwerengero cha kupulumuka chinawonjezeka kwambiri, koma chiopsezo chotaya magazi mu ubongo chinawonjezekanso.Pambuyo pake
Mayesero azachipatala a odwala 1222 omwe ali ndi vuto la ischemic stroke adatsimikizira kuti pambuyo pa maola atatu
Ancelose saloledwa kulandira chithandizo.1…. United States ndi Canada idasindikizidwa mu 2009
Zikwapu 500 zokhudza mayiko 12 ndi zigawo kuphatikiza Canada ndi Australia
kudwala
Nthawi yotumiza: Feb-26-2023