Kudzipatula kwa anticoagulant ndi fibrinolytic zigawo za Agkistrodon halys venom ndi zotsatira zake pamagazi coagulation system.

Kuphunzira zotsatira za thrombin ngati enzyme ndi plasmin olekanitsidwa ndi ululu wa Agkistrodon acutus pa magazi coagulation dongosolo Njira: Thrombin monga enzyme ndi plasmin anali olekanitsidwa ndi kuyeretsedwa ku Agkistrodon acutus venom ndi DEAE Sepharose CL-6B ndi Sephadex G-75 chromatography, ndi zotsatira zake pa coagulation system zinawonedwa kudzera mu kuyesera kwa vivoMu vivo kuyesa kunasonyeza kuti thrombin ngati enzyme ndi plasmin kuchokera ku Agkistrodon acutus venom akhoza kutalikitsa nthawi yonse ya magazi kuundana, kulowetsa nthawi ya prothrombin, nthawi ya thrombin ndi nthawi ya prothrombin, ndi kuchepetsa zomwe zili mu fibrinogen, koma zotsatira za thrombin ngati enzyme zinali zamphamvu. , Komabe, puloteni ya fibrinolytic inasonyeza zotsatira za anticoagulant pokhapokha pa mlingo waukulu, ndipo kuphatikiza kwa awiriwo kunali bwino kuposa ntchito yawo imodzi.Kutsiliza: Thrombin ngati enzyme ndi fibrinolytic enzyme yochokera ku Agkistrodon acutus venom ali ndi