Pachimake kawopsedwe wa fibrinolytic enzyme popanda magazi ntchito kuchokera Agkistrodon acutus venom

Chigawo chatsopano cha AA-MP-I chinapatulidwa ku Agkistrodon acutus venom ndi thiophilic chromatography, Sephadex G-75, gel wabuluu ndi POROS HQ 20 ion exchange chromatography.Enzyme ndi puloteni ya monomer yokhala ndi molekyulu yolemera 22.9 kDa, yokhala ndi isoelectric point ya 5.55, palibe gulu la shuga la ndale, ndipo mndandanda wake wa N-terminal ndi STEFQRYMEIVVDHSMVK.Zotsatira zikuwonetsa kuti ndi PI metalloproteinase yatsopano, yomwe imakhudzidwa ndi kutentha, imakhala ndi anticoagulant, anticoagulant yamphamvu kwambiri pa 40 ℃, ili ndi poizoni wa haemorrhagic, ndipo ilibe phospholipase A: ntchito.