Kugwiritsa Ntchito Utsi Wa Njoka Kuletsa Kutuluka Kwa Magazi Ndi Kuletsa Kutulutsa Chithunzi Chowonetsedwa

Kugwiritsa Ntchito Utsi Wa Njoka Kuletsa Kutaya Magazi Ndi Anticoagulation

Kufotokozera Kwachidule:

Mu 1981, defibrase yotengedwa ndi kupangidwa ndi Kunming Institute of Zoology, Yunnan, China, ku chiwopsezo cha njoka ya pentameter yaku China idadutsa kuwunika kwaukadaulo ndipo idagwiritsidwa ntchito pochiza milandu ya 333 ya mitsempha yamagazi, kuphatikiza milandu 242 ya thrombosis yaubongo. mlingo wogwira mtima wa 86.4%.The agkistrodon agkistrodon acidase, yopangidwa ndi China Medical University ndi Shenyang Pharmaceutical College, yakhala ikugwiritsidwa ntchito pochiza occlusives ya mitsempha ndi zotsatira zogwira mtima zachipatala.Njoka poizoni Laboratory ya China Medical University anayamba njoka ya njoka antacid enzyme, amene angathe kuchepetsa lipids magazi, dilate mitsempha, kuchepetsa zili thrombin m'magazi, kuonjezera prostacyclin, ndi kumasuka yosalala minofu ya mitsempha.Ndikoyenera kwa anticoagulant thrombolytic kukonzekera.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

1. "defibrase" yotengedwa ndikupangidwa kuchokera ku poizoni wa pentapodes waku China idavomerezedwa ndi Kunming Institute of Zoology, Yunnan, China mu 1981. Idagwiritsidwa ntchito pochiza milandu ya 333 ya vascular thrombosis, kuphatikiza milandu 242 ya cerebral thrombosis, mphamvu ya 86.4%.
2. Agkistrodon agkistrodon acidase, yopangidwa pamodzi ndi China Medical University ndi Shenyang Pharmaceutical College, yapeza zotsatira zogwira mtima zachipatala pochiza mitsempha ya mitsempha.
3. Njoka Njoka Laboratory ya China Medical University anayamba njoka ya njoka antacid enzyme, amene angathe kuchepetsa lipids magazi, dilate mitsempha, kuchepetsa zili thrombin m'magazi, kuwonjezera prostacyclin, ndi kumasuka yosalala minofu ya mitsempha.Ndikoyenera kwa anticoagulant thrombolytic kukonzekera.
4. Ululu wa njoka wotsutsa masitepe asanu
Antivenomous snake serum ndi mtundu wa mankhwala, womwe ndi mankhwala opangidwa kuchokera kumadzi am'madzi a akavalo otetezedwa ndi poizoni wa agkistrodon (agkistrodon), wogayidwa ndi enzyme ndikutulutsa mchere.Muli 2000U antivenomous njoka seramu.Mtundu uwu umakonzedwa ndi kugayidwa kwa enzyme ndi mchere wotuluka mumadzi am'madzi a akavalo otetezedwa ndi poizoni wa A. agkistrodon.

5. Makampani-yunivesite-kafukufuku mgwirizano
Mashan Longshe Snake Industry Co., Ltd. yagwirizana ndi njoka ya njoka ya Venom Institute ya Guangxi Medical University kuti ipereke utsi wamtundu wapamwamba wa njoka kwa nthawi yayitali, womwe umagwiritsidwa ntchito pophunzira za biochemistry, molecular biology ndi pharmacology ya mapuloteni a njoka ya njoka, ndi watsogolera ntchito zoposa 10 monga National Natural Science Foundation ndi Guangxi Science and Technology Department Project.Yapambana mphotho yachiwiri ya Guangxi Science and Technology Progress Award ndi mphotho yachitatu ya Guangxi Science and Technology Progress Award.

6. Njoka hemagglutinin ndi hemostatic wothandizila ndi thrombin kinase-ngati zotsatira, amene akhoza kusandulika fibrin ndi hydrolyzing fibrinogen, motero kupititsa patsogolo coagulation thupi;Mankhwalawa alinso ndi ntchito yopititsa patsogolo kuphatikizika kwa mapulateleti, omwe angayambitse kusanjika kosasinthika kwa mapulateleti, motero kumapangitsa kuti magazi aziyenda bwino, koma sizilimbikitsa kuphatikizika kwa mapulateleti m'mitsempha yamagazi.
Hemocoagulation ya agkistrodon agkistrodon ngati chithandizo cha hemostasis ya bala lapamwamba pa opaleshoni.